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P300-CBP PROTEIN
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DeCS
Descriptor
English
:
p300-CBP Transcription Factors
Descriptor
Spanish
:
Factores de Transcripción p300-CBP
Descriptor
Portuguese
:
Fatores de Transcrição de p300-CBP
Synonyms
English
:
Coactivator, p300-CBP
Transcription Factors, p300-CBP
p300 CBP Coactivator
p300 CBP Protein
p300 CBP Transcription Factors
p300-CBP Coactivator
p300-CBP Protein
Tree Number:
D08.811.913.050.134.415.500.575
D12.776.930.680
Definition
English
:
A
family
of
histone acetyltransferases
that is structurally-related to
CREB-BINDING PROTEIN
and to
E1A-ASSOCIATED P300 PROTEIN
. They function as transcriptional coactivators by bridging between DNA-binding
TRANSCRIPTION FACTORS
and the basal transcription
machinery
. They also modify
transcription factors
and
CHROMATIN
through
ACETYLATION.
History Note
English
:
2006(1994)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50671
Unique Identifier:
D050880
Occurrence in VHL
:
Similar:
DeCS